Endocrine Abstracts

Background: Menopause is associated to body composition transformations, such as an increase in total fat mass (obesity), central fat mass and a decrease in lean body mass (sarcopenia). Body fat distribution also changes with age, with an increase in visceral abdominal fat and a decrease in subcutaneous abdominal fat. Moreover, an increase in visceral fat may lead to increase the secretion of pro-inflammatory adipokines that further promote insulin resistance as well as potent...